Background: Urosepsis is a catastrophic complication, which can easily develop into septic shock and lead to death if\nnot diagnosed early and effectively treated in time. However, there is a lack of evidence on the risk factors and\noutcomes in calculous pyonephrosis patients. Therefore, this study was conducted to identify risk factors and\noutcomes of intra- and postoperative urosepsis in this particular population.\nMethods: Clinical data of 287 patients with calculous pyonephrosis were collected. In the univariate and\nmultivariate analysis, all patients were divided into urosepsis group and non-urosepsis group. The diagnosis\nof urosepsis was mainly on the basis of the criteria of American College of Chest Physicians (ACCP)/Society\nof Critical Care Medicine (SCCM). Patient characteristics and outcomes data were analyzed, and risk factors\nwere assessed by binary logistic regression analysis.\nResults: Of 287 patients, 41 (14.3%) acquired urosepsis. Univariate analysis showed that white blood cell (WBC\n> 10*10^9/L) before surgery (P = 0.027), surgery types (P = 0.009), hypotension during surgery (P < 0.001) and urgent\nsurgery (P < 0.001) were associated with intra- and postoperative urosepsis for calculous pyonephrosis patients. In\nmultivariate analysis, hypotension during surgery and urgent surgery were closely related to intra- and postoperative\nurosepsis. Outcome analysis suggested that patients developing urosepsis had a longer intensive care unit (ICU) stay\nand postoperative hospital stay and higher mortality.\nConclusions: Hypotension during surgery and urgent surgery were risk factors of intra- and postoperative urosepsis for\ncalculous pyonephrosis patients, which may lead to a prolonged ICU stay, postoperative hospital stay and higher\nmortality.
Loading....